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名稱: | anti- CD86 antibody |
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貨號: | FNab01504 |
適應(yīng)種屬: | 人源,大鼠,小鼠 |
規(guī)格: | 100ug(微克) |
狀態(tài): | 液體 |
純化方法: | 免疫親和純化 |
純度: | 經(jīng)DSD-PAGE分析,純度大于95% |
宿主: | 兔 |
亞型: | lgG |
存儲: | 用添加了0.02%疊氮化鈉和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12個月(避免反復(fù)凍融) |
免疫原: | CD86 molecule |
免疫原別稱: | Activation B7 2 antigen antibody, B7 2 antibody, B70 antibody, BU63 antibody, CD28LG2 antibody, CD86 antibody, CD86 molecule antibody, CTLA 4 counter receptor B7.2 antibody, FUN 1 antibody, LAB72 antibody |
分子量: | 75 kDa |
驗(yàn)證應(yīng)用: | ELISA, WB,IHC,IF |
建議稀釋比例: | WB: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:20-1:200 |
UniProt ID: | P42081 |
克隆性: | 多克隆 |
背景介紹: | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.(Microbial infection) Acts as a receptor for adenovirus subgroup B. |
圖像: | ![]() Immunofluorescent analysis of RAW264.7 cells using FNab01504 ( CD86 Antibody) at dilution of 1:50。 ![]() Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01504(CD86 Antibody) at dilution of 1:200. heat mediated antigen retrieved with Tris-EDTA buffer(pH9)。 ![]() Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01504(CD86 antibody) at dilution of 1:500。 |