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產(chǎn)品詳情
| 名稱： | anti- ERp57/ERp60 antibody |
|---|---|
| 貨號： | FNab02858 |
| 適應(yīng)種屬： | 人源,大鼠,小鼠 |
| 規(guī)格： | 100ug(微克) |
| 狀態(tài)： | 液體 |
| 純化方法： | 免疫親和純化 |
| 純度： | 經(jīng)SDS-PAGE分析,純度大于95% |
| 宿主： | 兔 |
| 亞型： | lgG |
| 存儲： | 用添加了0.02%疊氮化鈉和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12個(gè)月（避免反復(fù)凍融） |
| 免疫原： | protein disulfide isomerase family A, member 3 |
| 免疫原別稱： | 58 kDa microsomal protein antibody, Disulfide isomerase ER 60 antibody, ER protein 57 antibody, ER protein 60 antibody, ER60 antibody, ERp57 antibody, ERp60 antibody, ERp61 antibody, GRP57 antibody, GRP58 antibody, HsT17083 antibody, P58 antibod |
| 分子量： | 57 kDa |
| 驗(yàn)證應(yīng)用： | ELISA, WB, IHC, IF, FC, IP |
| 建議稀釋比例： | WB: 1:500-1:2400; IP: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| UniProt ID： | P30101 |
| 克隆性： | 多克隆 |
| 背景介紹： | PDIA3, also named as P58, ER60, ERp57, ERp60, ERp61, GRP57, GRP58 and PI-PLC, is a member of the PDI family, participates in the oxidation, reduction, and isomerization of disulfide bonds for correct folding of secretory proteins before modification and transport in the endoplasmic reticulum. It is associated with apoptosis or inhibition of cancer cell growth. PDIA3 was once thought to be a phospholipase; however, it has been demonstrated that this protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and PDIA3 mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. |
| 圖像： |  Immunofluorescent analysis of HepG2 cells, using PDIA3 antibody FNab02858 at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye)。
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