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產(chǎn)品詳情
| 名稱： | anti- HSP90 antibody |
|---|---|
| 貨號： | FNab04052 |
| 適應(yīng)種屬： | 人源,大鼠,小鼠 |
| 規(guī)格： | 100ug(微克) |
| 狀態(tài)： | 液體 |
| 純化方法： | 蛋白A/G柱純化 |
| 純度： | 經(jīng)SDS-PAGE分析,純度大于95% |
| 宿主： | 小鼠 |
| 亞型： | IgG1 |
| 存儲(chǔ)： | 用添加了0.02%疊氮化鈉和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12個(gè)月（避免反復(fù)凍融） |
| 免疫原： | heat shock protein 90kDa alpha(cytosolic), class A member 1 |
| 免疫原別稱： | HSP 86 antibody, HSP86 antibody, Hsp89 antibody, HSP89A antibody, HSP90 antibody, HSP90A antibody, HSP90AA1 antibody, HSP90N antibody, HSPC1 antibody, HSPCA antibody, HSPCAL1 antibody, HSPCAL4 antibody, HSPN antibody, LAP2 antibody |
| 分子量： | 90 kDa |
| 驗(yàn)證應(yīng)用： | ELISA, WB, IHC, FC |
| 建議稀釋比例： | WB: 1:1000-1:8000; IHC: 1:50-1:500 |
| UniProt ID： | P07900 |
| 克隆性： | 單克隆 |
| 背景介紹： | HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application. |
| 圖像： |  Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab04052(HSP90 Antibody) at dilution of 1:200。
|
