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產(chǎn)品詳情
| 名稱： | anti- RAD51 antibody |
|---|---|
| 貨號(hào)： | FNab07079 |
| 適應(yīng)種屬： | 人源,大鼠,小鼠 |
| 規(guī)格： | 100ug(微克) |
| 狀態(tài)： | 液體 |
| 純化方法： | 免疫親和純化 |
| 純度： | 經(jīng)SDS-PAGE分析,純度大于95% |
| 宿主： | 兔 |
| 亞型： | lgG |
| 存儲(chǔ)： | 用添加了0.02%疊氮化鈉和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12個(gè)月（避免反復(fù)凍融） |
| 免疫原： | RAD51 homolog |
| 免疫原別稱： | RAD51A antibody, RECA antibody |
| 分子量： | 37 kDa |
| 驗(yàn)證應(yīng)用： | ELISA, WB, IP,IHC |
| 建議稀釋比例： | WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500 |
| UniProt ID： | Q06609 |
| 克隆性： | 多克隆 |
| 背景介紹： | Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. |
| 圖像： |  Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab07079(RAD51 Antibody) at dilution of 1:200。
|
