服務(wù)熱線
15623758226
聯(lián)系方式
- 手機：15623758226
- 電話：027-65524773
- Q Q：3038053592
- 郵箱：3038053592@qq.com
- 地址：武漢東湖新技術(shù)開發(fā)區(qū)高新二路388號武漢光谷國際生物醫(yī)藥企業(yè)加速器1.2期C22棟一層、二層
發(fā)布時間：2023-08-30 15:16?? 咨詢量：
聯(lián)系客服 027-65524773
資料下載sales2@fn-test.com
產(chǎn)品詳情
| 名稱： | anti- XRCC5/Ku80 antibody |
|---|---|
| 貨號： | FNab09555 |
| 適應(yīng)種屬： | 人源 |
| 規(guī)格： | 100ug(微克) |
| 狀態(tài)： | 液體 |
| 純化方法： | 免疫親和純化 |
| 純度： | 經(jīng)SDS-PAGE分析,純度大于95% |
| 宿主： | 兔 |
| 亞型： | lgG |
| 存儲： | 用添加了0.02%疊氮化鈉和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12個月（避免反復(fù)凍融） |
| 免疫原： | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 免疫原別稱： | 86 kDa subunit of Ku antigen antibody, CTC85 antibody, CTCBF antibody, DNA repair protein XRCC5 antibody, FLJ39089 antibody, G22P2 antibody, KARP 1 antibody, KARP1 antibody, Ku80 antibody, Ku86 antibody, KUB2 antibody, NFIV antibody, Nuclear fac |
| 分子量： | Refer to figures |
| 驗證應(yīng)用： | ELISA, WB, IHC |
| 建議稀釋比例： | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| UniProt ID： | P13010 |
| 克隆性： | 多克隆 |
| 背景介紹： | The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
| 圖像： |  Immunohistochemistry of paraffin-embedded human colon cancer using FNab09555(XRCC5 antibody) at dilution of 1:100。
|
