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產品詳情
| 名稱： | anti- PARP1 antibody |
|---|---|
| 貨號： | FNab09939 |
| 適應種屬： | 人源,大鼠,小鼠 |
| 規(guī)格： | 100ug(微克) |
| 狀態(tài)： | 液體 |
| 純化方法： | 蛋白A/G柱純化 |
| 純度： | 經SDS-PAGE分析,純度大于95% |
| 宿主： | 小鼠 |
| 亞型： | IgG1 |
| 存儲： | 用添加了0.02%疊氮化鈉和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12個月（避免反復凍融） |
| 免疫原： | poly (ADP-ribose) polymerase 1 |
| 免疫原別稱： | ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, pADPRT 1 antibody, PARP antibody, PARP 1 antibody, PARP1 antibody, poly (ADP ribose) polymerase 1 antibody, Poly [ADP ribose] polymerase 1 antibody, Poly[ADP ribose] synthase 1 antibody, PPOL an |
| 分子量： | 115 kDa, 89 kDa |
| 驗證應用： | ELISA, WB, IHC, IF |
| 建議稀釋比例： | WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500 |
| UniProt ID： | P09874 |
| 克隆性： | 單克隆 |
| 背景介紹： | PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis. |
| 圖像： |  Immunofluorescent analysis of HeLa cells using FNab09939 (PARP1 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L)。
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