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名稱: | anti- PCNA antibody |
---|---|
貨號: | FNab06215 |
適應(yīng)種屬: | 人源,大鼠,小鼠 |
規(guī)格: | 100ug(微克) |
狀態(tài): | 液體 |
純化方法: | 免疫親和純化 |
純度: | 經(jīng)SDS-PAGE分析,純度大于95% |
宿主: | 兔 |
亞型: | lgG |
存儲: | 用添加了0.02%疊氮化鈉和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12個月(避免反復(fù)凍融) |
免疫原: | proliferating cell nuclear antigen |
免疫原別稱: | Proliferating cell nuclear antigen antibody, Cyclin antibody |
分子量: | 38 kDa |
驗證應(yīng)用: | ELISA, WB, IHC |
建議稀釋比例: | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
UniProt ID: | P12004 |
克隆性: | 多克隆 |
背景介紹: | The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
圖像: | ![]() Immunohistochemistry of paraffin-embedded human stomach cancer using FNab06215(PCNA antibody) at dilution of 1:50。 ![]() A431 cells were subjected to SDS PAGE followed by western blot with FNab06215(PCNA antibody) at dilution of 1:1000。 |